Decay-Accelerating Factor Restrains Complement Activation and Delays Progression of Murine cBSA-Induced Membranous Nephropathy

KEY POINTS: In a murine model of cationic bovine serum albumin (cBSA)–induced membranous nephropathy (MN), complement regulator decay-accelerating factor is upregulated and restrains complement activation. Studies using genetic deletion or pharmacological antagonism of C3aR indicate that the main ef...

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Detalles Bibliográficos
Autores principales: Budge, Kelly L, Verlato, Alberto, Bin, Sofia, Salem, Fadi E., Perin, Laura, La Manna, Gaetano, Zaza, Gianluigi, Fiaccadori, Enrico, Cantarelli, Chiara, Cravedi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Nephrology 2023
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371372/
https://www.ncbi.nlm.nih.gov/pubmed/37036696
http://dx.doi.org/10.34067/KID.0000000000000122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371372/
https://www.ncbi.nlm.nih.gov/pubmed/37036696
http://dx.doi.org/10.34067/KID.0000000000000122

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