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Patterns of transcription factor binding and epigenome at promoters allow interpretable predictability of multiple functions of non-coding and coding genes

Understanding the biological roles of all genes only through experimental methods is challenging. A computational approach with reliable interpretability is needed to infer the function of genes, particularly for non-coding RNAs. We have analyzed genomic features that are present across both coding...

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Detalles Bibliográficos
Autores principales: Chandra, Omkar, Sharma, Madhu, Pandey, Neetesh, Jha, Indra Prakash, Mishra, Shreya, Kong, Say Li, Kumar, Vibhor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371796/
https://www.ncbi.nlm.nih.gov/pubmed/37520281
http://dx.doi.org/10.1016/j.csbj.2023.07.014