Towards advanced bioprocess optimization: A multiscale modelling approach

Mammalian cells produce up to 80 % of the commercially available therapeutic proteins, with Chinese Hamster Ovary (CHO) cells being the primary production host. Manufacturing involves a train of reactors, the last of which is typically run in fed-batch mode, where cells grow and produce the required...

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Detalles Bibliográficos
Autores principales: Monteiro, Mariana, Fadda, Sarah, Kontoravdi, Cleo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371800/
https://www.ncbi.nlm.nih.gov/pubmed/37520284
http://dx.doi.org/10.1016/j.csbj.2023.07.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371800/
https://www.ncbi.nlm.nih.gov/pubmed/37520284
http://dx.doi.org/10.1016/j.csbj.2023.07.003

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