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Antitumor activity of 5-fluorouracil polymeric nanogel synthesized by gamma radiation on a rat model of colon carcinoma: a proposed mechanism

The use of 5-fluorouracil (5-FU) is associated with multifaceted challenges and poor pharmacokinetics. Accordingly, our study was designed to prepare 5-FU nanogel as a new form of the colon cancer chemotherapeutic drug 5-FU using polyacrylic acid and gelatin hybrid nanogel as efficient drug carriers...

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Detalles Bibliográficos
Autores principales: Abo-Zaid, Omayma A. R., Moawed, Fatma S. M., Barakat, Wael E. M., Ghobashy, Mohamed Mohamady, Ahmed, Esraa S. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371941/
https://www.ncbi.nlm.nih.gov/pubmed/37493814
http://dx.doi.org/10.1007/s12672-023-00733-z