Metabolic modelling-based in silico drug target prediction identifies six novel repurposable drugs for melanoma

Despite high initial response rates to targeted kinase inhibitors, the majority of patients suffering from metastatic melanoma present with high relapse rates, demanding for alternative therapeutic options. We have previously developed a drug repurposing workflow to identify metabolic drug targets t...

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Detalles Bibliográficos
Autores principales: Bintener, Tamara, Pacheco, Maria Pires, Philippidou, Demetra, Margue, Christiane, Kishk, Ali, Del Mistro, Greta, Di Leo, Luca, Moscardó Garcia, Maria, Halder, Rashi, Sinkkonen, Lasse, De Zio, Daniela, Kreis, Stephanie, Kulms, Dagmar, Sauter, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372000/
https://www.ncbi.nlm.nih.gov/pubmed/37495601
http://dx.doi.org/10.1038/s41419-023-05955-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372000/
https://www.ncbi.nlm.nih.gov/pubmed/37495601
http://dx.doi.org/10.1038/s41419-023-05955-1

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