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Metabolic modelling-based in silico drug target prediction identifies six novel repurposable drugs for melanoma
Despite high initial response rates to targeted kinase inhibitors, the majority of patients suffering from metastatic melanoma present with high relapse rates, demanding for alternative therapeutic options. We have previously developed a drug repurposing workflow to identify metabolic drug targets t...
Autores principales: | Bintener, Tamara, Pacheco, Maria Pires, Philippidou, Demetra, Margue, Christiane, Kishk, Ali, Del Mistro, Greta, Di Leo, Luca, Moscardó Garcia, Maria, Halder, Rashi, Sinkkonen, Lasse, De Zio, Daniela, Kreis, Stephanie, Kulms, Dagmar, Sauter, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372000/ https://www.ncbi.nlm.nih.gov/pubmed/37495601 http://dx.doi.org/10.1038/s41419-023-05955-1 |
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