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A novel approach to finding conserved features in low-variability gene alignments characterises RNA motifs in SARS-CoV and SARS-CoV-2

Collections of genetic sequences belonging to related organisms contain information on the evolutionary constraints to which the organisms have been subjected. Heavily constrained regions can be investigated to understand their roles in an organism’s life cycle, and drugs can be sought to disrupt th...

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Detalles Bibliográficos
Autores principales: Skittrall, Jordan P., Irigoyen, Nerea, Brierley, Ian, Gog, Julia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372003/
https://www.ncbi.nlm.nih.gov/pubmed/37495730
http://dx.doi.org/10.1038/s41598-023-39207-1