5-Iodotubercidin sensitizes cells to RIPK1-dependent necroptosis by interfering with NFκB signaling

Receptor-interacting protein kinases (RIPK)-1 and -3 play crucial roles in cell fate decisions and are regulated by multiple checkpoint controls. Previous studies have identified IKK1/2- and p38/MK2-dependent checkpoints that phosphorylate RIPK1 at different residues to inhibit its activation. In th...

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Detalles Bibliográficos
Autores principales: Chauhan, Chanchal, Kraemer, Andreas, Knapp, Stefan, Windheim, Mark, Kotlyarov, Alexey, Menon, Manoj B., Gaestel, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372004/
https://www.ncbi.nlm.nih.gov/pubmed/37495567
http://dx.doi.org/10.1038/s41420-023-01576-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372004/
https://www.ncbi.nlm.nih.gov/pubmed/37495567
http://dx.doi.org/10.1038/s41420-023-01576-x

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