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Based on network pharmacology, gastrodin attenuates hypertension-induced vascular smooth muscle cell proliferation and PI3K/AKT pathway activation

The effects and underlying mechanisms of gastrodin treatment on hypertensive vascular dysfunction and proliferation of vascular smooth muscle cells (VSMCs) were determined in vitro and in vivo. Using a pharmacological target network interaction analysis, 151 common targets and a PPI network were ide...

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Detalles Bibliográficos
Autores principales: Shen, Aling, Wu, Meizhu, Ali, Farman, Guo, Zhi, Fang, Yi, Zhou, Yuting, Zhang, Siyu, Zhang, Wenqiang, Wen, Ying, Yu, Min, Peng, Jun, Chen, Keji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372005/
https://www.ncbi.nlm.nih.gov/pubmed/37495624
http://dx.doi.org/10.1038/s41598-023-39202-6