Cargando…
Based on network pharmacology, gastrodin attenuates hypertension-induced vascular smooth muscle cell proliferation and PI3K/AKT pathway activation
The effects and underlying mechanisms of gastrodin treatment on hypertensive vascular dysfunction and proliferation of vascular smooth muscle cells (VSMCs) were determined in vitro and in vivo. Using a pharmacological target network interaction analysis, 151 common targets and a PPI network were ide...
Autores principales: | Shen, Aling, Wu, Meizhu, Ali, Farman, Guo, Zhi, Fang, Yi, Zhou, Yuting, Zhang, Siyu, Zhang, Wenqiang, Wen, Ying, Yu, Min, Peng, Jun, Chen, Keji |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372005/ https://www.ncbi.nlm.nih.gov/pubmed/37495624 http://dx.doi.org/10.1038/s41598-023-39202-6 |
Ejemplares similares
-
Gastrodin attenuates angiotensin II-induced vascular contraction and MLCK/p-MLC(2) pathway activation
por: Guo, Zhi, et al.
Publicado: (2023) -
Gastrodin attenuates renal injury and collagen deposition via suppression of the TGF-β1/Smad2/3 signaling pathway based on network pharmacology analysis
por: Wen, Ying, et al.
Publicado: (2023) -
Gastrodin inhibits cell proliferation in vascular smooth muscle cells and attenuates neointima formation in vivo
por: ZHU, LIHUA, et al.
Publicado: (2012) -
Quercetin inhibits angiotensin II-induced vascular smooth muscle cell proliferation and activation of JAK2/STAT3 pathway: A target based networking pharmacology approach
por: Wang, Di, et al.
Publicado: (2022) -
Isoliensinine Attenuates Renal Fibrosis and Inhibits TGF-β1/Smad2/3 Signaling Pathway in Spontaneously Hypertensive Rats
por: Yao, Mengying, et al.
Publicado: (2023)