Molecular basis of GDF15 induction and suppression by drugs in cardiomyocytes and cancer cells toward precision medicine

GDF15 has recently emerged as a key driver of the development of various disease conditions including cancer cachexia. Not only the tumor itself but also adverse effects of chemotherapy have been reported to contribute to increased GDF15. Although regulation of GDF15 transcription by BET domain has...

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Detalles Bibliográficos
Autores principales: Winter, Lisa-Maria, Reinhardt, Diana, Schatter, Ariane, Tissen, Vivien, Wiora, Heike, Gerlach, Daniel, Tontsch-Grunt, Ulrike, Colbatzky, Florian, Stierstorfer, Birgit, Yun, Seong-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372009/
https://www.ncbi.nlm.nih.gov/pubmed/37495707
http://dx.doi.org/10.1038/s41598-023-38450-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372009/
https://www.ncbi.nlm.nih.gov/pubmed/37495707
http://dx.doi.org/10.1038/s41598-023-38450-w

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