Cargando…

Enhancing tylosin production by combinatorial overexpression of efflux, SAM biosynthesis, and regulatory genes in hyperproducing Streptomyces xinghaiensis strain

Tylosin is a 16-membered macrolide antibiotic widely used in veterinary medicine to control infections caused by Gram-positive pathogens and mycoplasmas. To improve the fermentation titer of tylosin in the hyperproducing Streptomyces xinghaiensis strain TL01, we sequenced its whole genome and identi...

Descripción completa

Detalles Bibliográficos
Autores principales: Dai, Penghui, Qin, Yuyao, Li, Luyuan, Li, Haidi, Lv, Lihuo, Xu, Danying, Song, Yuqing, Huang, Tingting, Lin, Shuangjun, Deng, Zixin, Tao, Meifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372049/
https://www.ncbi.nlm.nih.gov/pubmed/37519989
http://dx.doi.org/10.1016/j.synbio.2023.07.002