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Histone deacetylase inhibitors inhibit lung adenocarcinoma metastasis via HDAC2/YY1 mediated downregulation of Cdh1

Metastasis is a leading cause of mortality in patients with lung adenocarcinoma. Histone deacetylases have emerged as promising targets for anti-tumor drugs, with histone deacetylase inhibitors (HDACi) being an active area of research. However, the precise mechanisms by which HDACi inhibits lung can...

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Detalles Bibliográficos
Autores principales: Wang, Dongmei, Yang, Yixiao, Cao, Yuxiang, Meng, Meiyao, Wang, Xiaobo, Zhang, Zhengxun, Fu, Wei, Duan, Shichao, Tang, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372082/
https://www.ncbi.nlm.nih.gov/pubmed/37495623
http://dx.doi.org/10.1038/s41598-023-38848-6