Spatial lipidomics reveals brain region-specific changes of sulfatides in an experimental MPTP Parkinson’s disease primate model

Metabolism of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) to the neurotoxin MPP(+) in the brain causes permanent Parkinson’s disease-like symptoms by destroying dopaminergic neurons in the pars compacta of the substantia nigra in humans and non-human primates. However, the complete molecular...

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Detalles Bibliográficos
Autores principales: Kaya, Ibrahim, Nilsson, Anna, Luptáková, Dominika, He, Yachao, Vallianatou, Theodosia, Bjärterot, Patrik, Svenningsson, Per, Bezard, Erwan, Andrén, Per E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372136/
https://www.ncbi.nlm.nih.gov/pubmed/37495571
http://dx.doi.org/10.1038/s41531-023-00558-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372136/
https://www.ncbi.nlm.nih.gov/pubmed/37495571
http://dx.doi.org/10.1038/s41531-023-00558-1

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