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Paraganglioma with High Levels of Dopamine, Dopa Decarboxylase Suppression, Dopamine β-hydroxylase Upregulation and Intra-tumoral Melanin Accumulation: A Case Report with a Literature Review

OBJECT: Exclusively dopamine-producing pheochromocytoma/paraganglioma (PPGL) is an extremely rare subtype. In this condition, intratumoral dopamine β-hydroxylase (DBH), which controls the conversion of norepinephrine from dopamine, is impaired, resulting in suppressed norepinephrine and epinephrine...

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Detalles Bibliográficos
Autores principales: Nezu, Masahiro, Hirotsu, Yosuke, Amemiya, Kenji, Tateno, Toru, Takizawa, Soichi, Inoue, Masaharu, Mochizuki, Hitoshi, Hosaka, Kyoko, Chik, Constance, Oyama, Toshio, Omata, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372287/
https://www.ncbi.nlm.nih.gov/pubmed/36384901
http://dx.doi.org/10.2169/internalmedicine.0743-22