Pharmacological inhibition of protein S-palmitoylation suppresses osteoclastogenesis and ameliorates ovariectomy-induced bone loss

BACKGROUND: Excessive osteoclast formation disrupts bone homeostasis, thereby significantly contributing to pathological bone loss associated with a variety of diseases. Protein S-palmitoylation is a reversible post-translational lipid modification catalyzed by ZDHHC family of palmitoyl acyltransfer...

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Detalles Bibliográficos
Autores principales: Ma, Linghui, Zhang, Liwei, Liao, Zirui, Xiu, Chunmei, Luo, Xi, Luo, Na, Zhang, Lei, He, Guangxu, Chen, Jianquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372326/
https://www.ncbi.nlm.nih.gov/pubmed/37521493
http://dx.doi.org/10.1016/j.jot.2023.06.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372326/
https://www.ncbi.nlm.nih.gov/pubmed/37521493
http://dx.doi.org/10.1016/j.jot.2023.06.002

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