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Pharmacological inhibition of protein S-palmitoylation suppresses osteoclastogenesis and ameliorates ovariectomy-induced bone loss
BACKGROUND: Excessive osteoclast formation disrupts bone homeostasis, thereby significantly contributing to pathological bone loss associated with a variety of diseases. Protein S-palmitoylation is a reversible post-translational lipid modification catalyzed by ZDHHC family of palmitoyl acyltransfer...
Autores principales: | Ma, Linghui, Zhang, Liwei, Liao, Zirui, Xiu, Chunmei, Luo, Xi, Luo, Na, Zhang, Lei, He, Guangxu, Chen, Jianquan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chinese Speaking Orthopaedic Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372326/ https://www.ncbi.nlm.nih.gov/pubmed/37521493 http://dx.doi.org/10.1016/j.jot.2023.06.002 |
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