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Extensive multiregional urea elevations in a case-control study of vascular dementia point toward a novel shared mechanism of disease amongst the age-related dementias

INTRODUCTION: Vascular dementia (VaD) is one of the most common causes of dementia among the elderly. Despite this, the molecular basis of VaD remains poorly characterized when compared to other age-related dementias. Pervasive cerebral elevations of urea have recently been reported in several demen...

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Detalles Bibliográficos
Autores principales: Philbert, Sasha A., Xu, Jingshu, Scholefield, Melissa, Patassini, Stefano, Church, Stephanie J., Unwin, Richard D., Roncaroli, Federico, Cooper, Garth J. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372345/
https://www.ncbi.nlm.nih.gov/pubmed/37520429
http://dx.doi.org/10.3389/fnmol.2023.1215637