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Phosphatases maintain low catalytic activity of SGK1: DNA damage resets the balance in favor of phosphorylation
The serum- and glucocorticoid-induced kinase 1 (SGK1) promotes cell survival under stress conditions and facilitates the emergence of drug resistance in cancer. The underlying mechanisms of these observations are not fully understood. In this study, we found that SGK1 activity is suppressed by the a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372406/ https://www.ncbi.nlm.nih.gov/pubmed/37343701 http://dx.doi.org/10.1016/j.jbc.2023.104941 |