Human TLR8 induces inflammatory bone marrow erythromyeloblastic islands and anemia in SLE-prone mice

Anemia commonly occurs in systemic lupus erythematosus, a disease characterized by innate immune activation by nucleic acids. Overactivation of cytoplasmic sensors by self-DNA or RNA can cause erythroid cell death, while sparing other hematopoietic cell lineages. Whereas chronic inflammation is invo...

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Detalles Bibliográficos
Autores principales: Maria, Naomi I, Papoin, Julien, Raparia, Chirag, Sun, Zeguo, Josselsohn, Rachel, Lu, Ailing, Katerji, Hani, Syeda, Mahrukh M, Polsky, David, Paulson, Robert, Kalfa, Theodosia, Barnes, Betsy J, Zhang, Weijia, Blanc, Lionel, Davidson, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372407/
https://www.ncbi.nlm.nih.gov/pubmed/37495396
http://dx.doi.org/10.26508/lsa.202302241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372407/
https://www.ncbi.nlm.nih.gov/pubmed/37495396
http://dx.doi.org/10.26508/lsa.202302241

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