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Human TLR8 induces inflammatory bone marrow erythromyeloblastic islands and anemia in SLE-prone mice
Anemia commonly occurs in systemic lupus erythematosus, a disease characterized by innate immune activation by nucleic acids. Overactivation of cytoplasmic sensors by self-DNA or RNA can cause erythroid cell death, while sparing other hematopoietic cell lineages. Whereas chronic inflammation is invo...
Autores principales: | Maria, Naomi I, Papoin, Julien, Raparia, Chirag, Sun, Zeguo, Josselsohn, Rachel, Lu, Ailing, Katerji, Hani, Syeda, Mahrukh M, Polsky, David, Paulson, Robert, Kalfa, Theodosia, Barnes, Betsy J, Zhang, Weijia, Blanc, Lionel, Davidson, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372407/ https://www.ncbi.nlm.nih.gov/pubmed/37495396 http://dx.doi.org/10.26508/lsa.202302241 |
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