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Lack of polyamines leads to cotranslational degradation of the general stress factor RpoS in Escherichia coli

The specialized sigma factor RpoS mediates a general stress response in Escherichia coli and related bacteria, activating promoters that allow cells to survive stationary phase and many stresses. RpoS synthesis and stability are regulated at multiple levels. Translation of RpoS is positively regulat...

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Detalles Bibliográficos
Autores principales: Majdalani, Nadim, Chattopadhyay, Manas, Keller, Christopher, Gottesman, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372455/
https://www.ncbi.nlm.nih.gov/pubmed/37343699
http://dx.doi.org/10.1016/j.jbc.2023.104943