MLL4 Regulates the Progression of Non–Small-Cell Lung Cancer by Regulating the PI3K/AKT/SOX2 Axis

PURPOSE: Mixed-lineage leukemia protein 4 (MLL4/KMT2D) is a histone methyltransferase, and its mutation has been reported to be associated with a poor prognosis in many cancers, including lung cancer. We investigated the function of MLL4 in lung carcinogenesis. MATERIALS AND METHODS: RNA sequencing...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Qiu, Rongfang, Weng, Qiaoyou, Xu, Ziwei, Song, Jingjing, Zhao, Siyu, Meng, Miaomiao, Zhang, Dengke, Kong, Chunli, Wang, Hailin, Xu, Min, Zhao, Zhongwei, Ji, Jiansong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372590/
https://www.ncbi.nlm.nih.gov/pubmed/36701842
http://dx.doi.org/10.4143/crt.2022.1042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372590/
https://www.ncbi.nlm.nih.gov/pubmed/36701842
http://dx.doi.org/10.4143/crt.2022.1042

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