Efficacy of Olaparib in Treatment-Refractory, Metastatic Breast Cancer with Uncommon Somatic BRCA Mutations Detected in Circulating Tumor DNA

Poly(ADP-ribose) polymerase inhibitors have been shown dramatic responses in patients with BRCAness. However, clinical studies have been limited to breast cancer patients with germline mutations. Here, we describe a patient with metastatic breast cancer who had a rare BRCA1 somatic mutation (BRCA1 c...

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Detalles Bibliográficos
Autores principales: Yoon, Jung-Ki, Ahn, Jongseong, Kim, Sheehyun, Kim, Hwang-Phil, Kang, Jun-kyu, Bang, Duhee, Lim, Yoojoo, Kim, Tae-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372606/
https://www.ncbi.nlm.nih.gov/pubmed/36731462
http://dx.doi.org/10.4143/crt.2022.1529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372606/
https://www.ncbi.nlm.nih.gov/pubmed/36731462
http://dx.doi.org/10.4143/crt.2022.1529

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