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Single subanesthetic dose of ketamine produces delayed impact on brain [(18)F]FDG PET imaging and metabolic connectivity in rats

INTRODUCTION: Ketamine, a glutamate NMDA receptor antagonist, is suggested to act very rapidly and durably on the depressive symptoms including treatment-resistant patients but its mechanisms of action remain unclear. There is a requirement for non-invasive biomarkers, such as imaging techniques, wh...

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Detalles Bibliográficos
Autores principales: Chaib, Sarah, Bouillot, Caroline, Bouvard, Sandrine, Vidal, Benjamin, Zimmer, Luc, Levigoureux, Elise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372660/
https://www.ncbi.nlm.nih.gov/pubmed/37521685
http://dx.doi.org/10.3389/fnins.2023.1213941