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Small mitochondrial protein NERCLIN regulates cardiolipin homeostasis and mitochondrial ultrastructure
Cardiolipin (CL) is an essential phospholipid for mitochondrial structure and function. Here, we present a small mitochondrial protein, NERCLIN, as a negative regulator of CL homeostasis and mitochondrial ultrastructure. Primate-specific NERCLIN is expressed ubiquitously from the GRPEL2 locus on a t...
Autores principales: | Konovalova, Svetlana, Torregrosa-Muñumer, Rubén, Manjunath, Pooja, Liu, Xiaonan, Baral, Sundar, Fatima, Kaneez, Holopainen, Minna, Kvist, Jouni, Rajendran, Jayasimman, Yang, Yang, Varjosalo, Markku, Käkelä, Reijo, Somerharju, Pentti, Tyynismaa, Henna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372682/ https://www.ncbi.nlm.nih.gov/pubmed/37463214 http://dx.doi.org/10.1073/pnas.2210599120 |
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