The role of Plasmodium V-ATPase in vacuolar physiology and antimalarial drug uptake

To ensure their survival in the human bloodstream, malaria parasites degrade up to 80% of the host erythrocyte hemoglobin in an acidified digestive vacuole. Here, we combine conditional reverse genetics and quantitative imaging approaches to demonstrate that the human malaria pathogen Plasmodium fal...

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Detalles Bibliográficos
Autores principales: Alder, Arne, Sanchez, Cecilia P., Russell, Matthew R. G., Collinson, Lucy M., Lanzer, Michael, Blackman, Michael J., Gilberger, Tim-Wolf, Matz, Joachim M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372686/
https://www.ncbi.nlm.nih.gov/pubmed/37463201
http://dx.doi.org/10.1073/pnas.2306420120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372686/
https://www.ncbi.nlm.nih.gov/pubmed/37463201
http://dx.doi.org/10.1073/pnas.2306420120

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