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The role of Plasmodium V-ATPase in vacuolar physiology and antimalarial drug uptake
To ensure their survival in the human bloodstream, malaria parasites degrade up to 80% of the host erythrocyte hemoglobin in an acidified digestive vacuole. Here, we combine conditional reverse genetics and quantitative imaging approaches to demonstrate that the human malaria pathogen Plasmodium fal...
Autores principales: | Alder, Arne, Sanchez, Cecilia P., Russell, Matthew R. G., Collinson, Lucy M., Lanzer, Michael, Blackman, Michael J., Gilberger, Tim-Wolf, Matz, Joachim M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372686/ https://www.ncbi.nlm.nih.gov/pubmed/37463201 http://dx.doi.org/10.1073/pnas.2306420120 |
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