Lipid biosynthesis perturbation impairs endoplasmic reticulum–associated degradation

The relationship between lipid homeostasis and protein homeostasis (proteostasis) is complex and remains incompletely understood. We conducted a screen for genes required for efficient degradation of Deg1-Sec62, a model aberrant translocon-associated substrate of the endoplasmic reticulum (ER) ubiqu...

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Detalles Bibliográficos
Autores principales: Turk, Samantha M., Indovina, Christopher J., Miller, Jacob M., Overton, Danielle L., Runnebohm, Avery M., Orchard, Cade J., Tragesser-Tiña, Mary E., Gosser, Samantha K., Doss, Ellen M., Richards, Kyle A., Irelan, Courtney Broshar, Daraghmi, Mahmoud M., Bailey, Connor G., Niekamp, Julia M., Claypool, Kieran P., Engle, Sarah M., Buchanan, Bryce W., Woodruff, Kelsey A., Olesen, James B., Smaldino, Philip J., Rubenstein, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article Collection: Protein Synthesis and Degradation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372827/
https://www.ncbi.nlm.nih.gov/pubmed/37331602
http://dx.doi.org/10.1016/j.jbc.2023.104939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372827/
https://www.ncbi.nlm.nih.gov/pubmed/37331602
http://dx.doi.org/10.1016/j.jbc.2023.104939

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