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Reversing the PAI-1-induced fibrotic immune exclusion of solid tumor by multivalent CXCR4 antagonistic nano-permeator

Fibrosis is one of the key factors that lead to the immune exclusion of solid tumors. Although degradation of fiber is a promising strategy, its application was still bottlenecked by the side effects of causing metastasis, resulting in the failure of immunotherapy. Here, we developed an antimetastat...

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Detalles Bibliográficos
Autores principales: Dong, Jingwen, Zhu, Chenfei, Huang, Ying, Li, Quanhao, Li, Jing, Wang, Zheng, Wang, Yixin, Zhou, Zhanwei, Sun, Minjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372828/
https://www.ncbi.nlm.nih.gov/pubmed/37521859
http://dx.doi.org/10.1016/j.apsb.2022.12.012