Controlling antifungal activity with light: Optical regulation of fungal ergosterol biosynthetic pathway with photo-responsive CYP51 inhibitors

Invasive fungal infections (IFIs) have been associated with high mortality, highlighting the urgent need for developing novel antifungal strategies. Herein the first light-responsive antifungal agents were designed by optical control of fungal ergosterol biosynthesis pathway with photocaged triazole...

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Detalles Bibliográficos
Autores principales: Li, Zhuang, Liu, Na, Yang, Wanzhen, Tu, Jie, Huang, Yahui, Wang, Wei, Sheng, Chunquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372832/
https://www.ncbi.nlm.nih.gov/pubmed/37521860
http://dx.doi.org/10.1016/j.apsb.2023.02.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372832/
https://www.ncbi.nlm.nih.gov/pubmed/37521860
http://dx.doi.org/10.1016/j.apsb.2023.02.008

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