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Downregulation of VPS13C promotes cisplatin resistance in cervical cancer by upregulating GSTP1

Cisplatin resistance remains a major obstacle limiting the effectiveness of chemotherapy in cervical cancer. However, the underlying mechanism of cisplatin resistance is still unclear. In this study, we demonstrate that vacuolar protein sorting 13 homolog C (VPS13C) deficiency promotes cisplatin res...

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Detalles Bibliográficos
Autores principales: Tan, Xiangyu, Wang, Xueqian, Liao, Xueyao, Wang, Xin, Jiang, Zhichao, Liang, Wenjia, Cao, Chen, Gong, Danni, Hu, Zheng, Tian, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372835/
https://www.ncbi.nlm.nih.gov/pubmed/37520723
http://dx.doi.org/10.1016/j.isci.2023.107315