Monitoring Disassembly and Cargo Release of Phase-Separated Peptide Coacervates with Native Mass Spectrometry

[Image: see text] Engineering liquid–liquid phase separation (LLPS) of proteins and peptides holds great promise for the development of therapeutic carriers with intracellular delivery capability but requires accurate determination of their assembly properties in vitro, usually with fluorescently la...

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Detalles Bibliográficos
Autores principales: Cerrato, Carmine P., Leppert, Axel, Sun, Yue, Lane, David P., Arsenian-Henriksson, Marie, Miserez, Ali, Landreh, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372869/
https://www.ncbi.nlm.nih.gov/pubmed/37439740
http://dx.doi.org/10.1021/acs.analchem.3c02384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372869/
https://www.ncbi.nlm.nih.gov/pubmed/37439740
http://dx.doi.org/10.1021/acs.analchem.3c02384

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