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Trapping and retaining intermediates in glycosyltransferases

Glycosyltransferases (GTs) attach sugar molecules to a broad range of acceptors, generating a remarkable amount of structural diversity in biological systems. GTs are classified as either “retaining” or “inverting” enzymes. Most retaining GTs typically use an S(N)i mechanism. In a recent article in...

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Detalles Bibliográficos
Autor principal: Guerin, Marcelo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372902/
https://www.ncbi.nlm.nih.gov/pubmed/37394002
http://dx.doi.org/10.1016/j.jbc.2023.105006