Genome-Wide Methylation Profiling in 229 Patients With Crohn’s Disease Requiring Intestinal Resection: Epigenetic Analysis of the Trial of Prevention of Post-operative Crohn’s Disease (TOPPIC)

BACKGROUND & AIMS: DNA methylation alterations may provide important insights into gene-environment interaction in cancer, aging, and complex diseases, such as inflammatory bowel disease (IBD). We aim first to determine whether the circulating DNA methylome in patients requiring surgery may pred...

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Detalles Bibliográficos
Autores principales: Ventham, Nicholas T., Kennedy, Nicholas A., Kalla, Rahul, Adams, Alex T., Noble, Alexandra, Ennis, Holly, Mowat, Craig, Dunlop, Malcolm G., Satsangi, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372903/
https://www.ncbi.nlm.nih.gov/pubmed/37331566
http://dx.doi.org/10.1016/j.jcmgh.2023.06.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372903/
https://www.ncbi.nlm.nih.gov/pubmed/37331566
http://dx.doi.org/10.1016/j.jcmgh.2023.06.001

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