Genome-Wide Methylation Profiling in 229 Patients With Crohn’s Disease Requiring Intestinal Resection: Epigenetic Analysis of the Trial of Prevention of Post-operative Crohn’s Disease (TOPPIC)

BACKGROUND & AIMS: DNA methylation alterations may provide important insights into gene-environment interaction in cancer, aging, and complex diseases, such as inflammatory bowel disease (IBD). We aim first to determine whether the circulating DNA methylome in patients requiring surgery may pred...

Descripción completa

Detalles Bibliográficos
Autores principales: Ventham, Nicholas T., Kennedy, Nicholas A., Kalla, Rahul, Adams, Alex T., Noble, Alexandra, Ennis, Holly, Mowat, Craig, Dunlop, Malcolm G., Satsangi, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372903/
https://www.ncbi.nlm.nih.gov/pubmed/37331566
http://dx.doi.org/10.1016/j.jcmgh.2023.06.001

Ejemplares similares

Ejemplares similares