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Role of Nox4 in Mitigating Inflammation and Fibrosis in Dextran Sulfate Sodium–Induced Colitis

BACKGROUND & AIMS: Fibrosis development in ulcerative colitis is associated directly with the severity of mucosal inflammation, which increases the risk of colorectal cancer. The transforming growth factor-β (TGF-β) signaling pathway is an important source of tissue fibrogenesis, which is stimul...

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Detalles Bibliográficos
Autores principales: Lee, Yura, Kim, Sung-Hee, Jeong, Haengdueng, Kim, Kwang H., Jeon, Donghun, Cho, Yejin, Lee, Daekee, Nam, Ki Taek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372905/
https://www.ncbi.nlm.nih.gov/pubmed/37207801
http://dx.doi.org/10.1016/j.jcmgh.2023.05.002