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Isotoosendanin exerts inhibition on triple-negative breast cancer through abrogating TGF-β-induced epithelial–mesenchymal transition via directly targeting TGFβR1

As the most aggressive breast cancer, triple-negative breast cancer (TNBC) is still incurable and very prone to metastasis. The transform growth factor β (TGF-β)-induced epithelial–mesenchymal transition (EMT) is crucially involved in the growth and metastasis of TNBC. This study reported that a nat...

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Detalles Bibliográficos
Autores principales: Zhang, Jingnan, Zhang, Ze, Huang, Zhenlin, Li, Manlin, Yang, Fan, Wu, Zeqi, Guo, Qian, Mei, Xiyu, Lu, Bin, Wang, Changhong, Wang, Zhengtao, Ji, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372922/
https://www.ncbi.nlm.nih.gov/pubmed/37521871
http://dx.doi.org/10.1016/j.apsb.2023.05.006