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Novel Gastroprotective and Thermostable Cocrystal of Dimethyl Fumarate: Its Preparation, Characterization, and In Vitro and In Vivo Evaluation

[Image: see text] Crystallization has revolutionized the field of solid-state formulations by modulating the physiochemical and release profile of active pharmaceutical ingredients (APIs). Dimethyl fumarate (DF), an FDA-approved first-line drug for relapsing–remitting multiple sclerosis, has a subli...

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Detalles Bibliográficos
Autores principales: Alam, Qadir, Ganeshpurkar, Ankit, Singh, Sushil Kumar, Krishnamurthy, Sairam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10372935/
https://www.ncbi.nlm.nih.gov/pubmed/37521634
http://dx.doi.org/10.1021/acsomega.3c02463