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Neuroprotection afforded by targeting G protein-coupled receptors in heteromers and by heteromer-selective drugs
G protein-coupled receptors (GPCRs) are the target of hundreds of approved drugs. Although these drugs were designed to target individual receptors, it is becoming increasingly apparent that GPCRs interact with each other to form heteromers. Approved drug targets are often part of a GPCR heteromer,...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373065/ https://www.ncbi.nlm.nih.gov/pubmed/37521478 http://dx.doi.org/10.3389/fphar.2023.1222158 |