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Neuroprotection afforded by targeting G protein-coupled receptors in heteromers and by heteromer-selective drugs

G protein-coupled receptors (GPCRs) are the target of hundreds of approved drugs. Although these drugs were designed to target individual receptors, it is becoming increasingly apparent that GPCRs interact with each other to form heteromers. Approved drug targets are often part of a GPCR heteromer,...

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Detalles Bibliográficos
Autores principales: Franco, Rafael, Navarro, Gemma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373065/
https://www.ncbi.nlm.nih.gov/pubmed/37521478
http://dx.doi.org/10.3389/fphar.2023.1222158