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Bispecific antibody targeting TGF-β and PD-L1 for synergistic cancer immunotherapy

The PD-1/PD-L1 signaling pathway plays a crucial role in cancer immune evasion, and the use of anti-PD-1/PD-L1 antibodies represents a significant milestone in cancer immunotherapy. However, the low response rate observed in unselected patients and the development of therapeutic resistance remain ma...

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Detalles Bibliográficos
Autores principales: Li, Tianye, Wang, Xinrun, Niu, Mengke, Wang, Mingli, Zhou, Jianwei, Wu, Kongming, Yi, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373067/
https://www.ncbi.nlm.nih.gov/pubmed/37520520
http://dx.doi.org/10.3389/fimmu.2023.1196970