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Bispecific antibody targeting TGF-β and PD-L1 for synergistic cancer immunotherapy
The PD-1/PD-L1 signaling pathway plays a crucial role in cancer immune evasion, and the use of anti-PD-1/PD-L1 antibodies represents a significant milestone in cancer immunotherapy. However, the low response rate observed in unselected patients and the development of therapeutic resistance remain ma...
Autores principales: | Li, Tianye, Wang, Xinrun, Niu, Mengke, Wang, Mingli, Zhou, Jianwei, Wu, Kongming, Yi, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373067/ https://www.ncbi.nlm.nih.gov/pubmed/37520520 http://dx.doi.org/10.3389/fimmu.2023.1196970 |
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