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Genetic Encoding of Arylazopyrazole Phenylalanine for Optical Control of Translation

[Image: see text] An arylazopyrazole was explored for its use as an enhanced photoswitchable amino acid in genetic code expansion. This new unnatural amino acid was successfully incorporated into proteins in both bacterial and mammalian cells. While photocontrol of translation required pulsed irradi...

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Detalles Bibliográficos
Autores principales: Janosko, Chasity P., Shade, Olivia, Courtney, Taylor M., Horst, Trevor J., Liu, Melinda, Khare, Sagar D., Deiters, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373180/
https://www.ncbi.nlm.nih.gov/pubmed/37521667
http://dx.doi.org/10.1021/acsomega.3c03512