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Dual-Functional Drug Delivery System for Bisphosphonate-Related Osteonecrosis Prevention and Its Bioinspired Releasing Model and In Vitro Assessment

[Image: see text] Clindamycin (CDM)/geranylgeraniol (GGOH)-loaded plasma-treated mesoporous silica nanoparticles/carboxymethyl chitosan composite hydrogels (CHG60 and CHG120) were developed for the prevention of medication-related osteonecrosis of the jaw associated with bisphosphonates (MRONJ-B). T...

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Detalles Bibliográficos
Autores principales: Sungkhaphan, Piyarat, Thavornyutikarn, Boonlom, Muangsanit, Papon, Kaewkong, Pakkanun, Kitpakornsanti, Setthawut, Pornsuwan, Soraya, Singhatanadgit, Weerachai, Janvikul, Wanida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373185/
https://www.ncbi.nlm.nih.gov/pubmed/37521598
http://dx.doi.org/10.1021/acsomega.3c03440