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Characterization of thin film Parylene C device curvature and the formation of helices via thermoforming

In microfabricated biomedical devices, flexible, polymer substrates are becoming increasingly preferred over rigid, silicon substrates because of their ability to conform to biological tissue. Such devices, however, are fabricated in a planar configuration, which results in planar devices that do no...

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Autores principales: Thielen, Brianna, Meng, Ellis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOP Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373221/
https://www.ncbi.nlm.nih.gov/pubmed/37520061
http://dx.doi.org/10.1088/1361-6439/acdc33
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author Thielen, Brianna
Meng, Ellis
author_facet Thielen, Brianna
Meng, Ellis
author_sort Thielen, Brianna
collection PubMed
description In microfabricated biomedical devices, flexible, polymer substrates are becoming increasingly preferred over rigid, silicon substrates because of their ability to conform to biological tissue. Such devices, however, are fabricated in a planar configuration, which results in planar devices that do not closely match the shape of most tissues. Thermoforming, a process which can reshape thermoplastic polymers, can be used to transform flat, thin film, polymer devices with patterned metal features into complex three-dimensional (3D) geometries. This process extends the use of planar microfabrication to achieve 3D shapes which can more closely interface with the body. Common shapes include spheres, which can conform to the shape of the retina; cones, which can be used as a sheath to interface with an insertion stylet; and helices, which can be wrapped around nerves, blood vessels, muscle fibers, or be used as strain relief feature. This work characterizes the curvature of thin film Parylene C devices with patterned metal features built with varying Parylene thicknesses and processing conditions. Device curvature is caused by film stress in each Parylene and metal layer, which is characterized experimentally and by a mathematical model which estimates the effects of device geometry and processing on curvature. Using this characterization, an optimized process to thermoform thin film Parylene C devices with patterned metal features into 0.25 mm diameter helices while preventing cracking in the polymer and metal was developed.
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spelling pubmed-103732212023-07-28 Characterization of thin film Parylene C device curvature and the formation of helices via thermoforming Thielen, Brianna Meng, Ellis J Micromech Microeng Paper In microfabricated biomedical devices, flexible, polymer substrates are becoming increasingly preferred over rigid, silicon substrates because of their ability to conform to biological tissue. Such devices, however, are fabricated in a planar configuration, which results in planar devices that do not closely match the shape of most tissues. Thermoforming, a process which can reshape thermoplastic polymers, can be used to transform flat, thin film, polymer devices with patterned metal features into complex three-dimensional (3D) geometries. This process extends the use of planar microfabrication to achieve 3D shapes which can more closely interface with the body. Common shapes include spheres, which can conform to the shape of the retina; cones, which can be used as a sheath to interface with an insertion stylet; and helices, which can be wrapped around nerves, blood vessels, muscle fibers, or be used as strain relief feature. This work characterizes the curvature of thin film Parylene C devices with patterned metal features built with varying Parylene thicknesses and processing conditions. Device curvature is caused by film stress in each Parylene and metal layer, which is characterized experimentally and by a mathematical model which estimates the effects of device geometry and processing on curvature. Using this characterization, an optimized process to thermoform thin film Parylene C devices with patterned metal features into 0.25 mm diameter helices while preventing cracking in the polymer and metal was developed. IOP Publishing 2023-09-01 2023-07-27 /pmc/articles/PMC10373221/ /pubmed/37520061 http://dx.doi.org/10.1088/1361-6439/acdc33 Text en © 2023 The Author(s). Published by IOP Publishing Ltd https://creativecommons.org/licenses/by/4.0/ Original content from this work may be used under the terms of the Creative Commons Attribution 4.0 license (https://creativecommons.org/licenses/by/4.0/) . Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI.
spellingShingle Paper
Thielen, Brianna
Meng, Ellis
Characterization of thin film Parylene C device curvature and the formation of helices via thermoforming
title Characterization of thin film Parylene C device curvature and the formation of helices via thermoforming
title_full Characterization of thin film Parylene C device curvature and the formation of helices via thermoforming
title_fullStr Characterization of thin film Parylene C device curvature and the formation of helices via thermoforming
title_full_unstemmed Characterization of thin film Parylene C device curvature and the formation of helices via thermoforming
title_short Characterization of thin film Parylene C device curvature and the formation of helices via thermoforming
title_sort characterization of thin film parylene c device curvature and the formation of helices via thermoforming
topic Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373221/
https://www.ncbi.nlm.nih.gov/pubmed/37520061
http://dx.doi.org/10.1088/1361-6439/acdc33
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