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Optogenetic cortical spreading depolarization induces headache-related behaviour and neuroinflammatory responses some prolonged in familial hemiplegic migraine type 1 mice

BACKGROUND: Cortical spreading depolarization (CSD), the neurophysiological correlate of the migraine aura, can activate trigeminal pain pathways, but the neurobiological mechanisms and behavioural consequences remain unclear. Here we investigated effects of optogenetically-induced CSDs on headache-...

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Detalles Bibliográficos
Autores principales: Dehghani, Anisa, Schenke, Maarten, van Heiningen, Sandra H., Karatas, Hulya, Tolner, Else A., van den Maagdenberg, Arn M. J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373261/
https://www.ncbi.nlm.nih.gov/pubmed/37495957
http://dx.doi.org/10.1186/s10194-023-01628-8