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Pre-T cell receptor localization and trafficking are independent of its signaling

Expression of the pre-T cell receptor (preTCR) is an important checkpoint during the development of T cells, an essential cell type of our adaptive immune system. The preTCR complex is only transiently expressed and rapidly internalized in developing T cells and is thought to signal in a ligand-inde...

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Detalles Bibliográficos
Autores principales: Smid, Andrei I., Garforth, Sam J., Obaid, Maryam S., Bollons, Hannah R., James, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373305/
https://www.ncbi.nlm.nih.gov/pubmed/37516909
http://dx.doi.org/10.1083/jcb.202212106