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Pre-T cell receptor localization and trafficking are independent of its signaling
Expression of the pre-T cell receptor (preTCR) is an important checkpoint during the development of T cells, an essential cell type of our adaptive immune system. The preTCR complex is only transiently expressed and rapidly internalized in developing T cells and is thought to signal in a ligand-inde...
Autores principales: | Smid, Andrei I., Garforth, Sam J., Obaid, Maryam S., Bollons, Hannah R., James, John R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373305/ https://www.ncbi.nlm.nih.gov/pubmed/37516909 http://dx.doi.org/10.1083/jcb.202212106 |
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