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Novel heavily fucosylated glycans as a promising therapeutic target in colorectal cancer

BACKGROUND: Colorectal cancer (CRC) is highly prevalent and lethal globally, and its prognosis remains unsatisfactory. Drug resistance is regarded as the main cause of treatment failure leading to tumor recurrence and metastasis. The overexpression of fucosylated epitopes, which are usually modifica...

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Detalles Bibliográficos
Autores principales: Tsai, Kuei-Yen, Chang, Yu-Jia, Huang, Chien-Yu, Prince, G. M. Shazzad Hossain, Chen, Hsin-An, Makondi, Precious Takondwa, Shen, Ying-Rou, Wei, Po-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373344/
https://www.ncbi.nlm.nih.gov/pubmed/37496011
http://dx.doi.org/10.1186/s12967-023-04363-5