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Role of pelitinib in the regulation of migration and invasion of hepatocellular carcinoma cells via inhibition of Twist1

BACKGROUND: Overexpression of Twist1, one of the epithelial-mesenchymal transition-transcription factors (EMT-TFs), is associated with hepatocellular carcinoma (HCC) metastasis. Pelitinib is known to be an irreversible epidermal growth factor receptor tyrosine kinase inhibitor that is used in clinic...

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Detalles Bibliográficos
Autores principales: Lee, Sewoong, Kang, Eunjeong, Lee, Unju, Cho, Sayeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373356/
https://www.ncbi.nlm.nih.gov/pubmed/37495969
http://dx.doi.org/10.1186/s12885-023-11217-2